Ecuador's envoy heads to Quito for Assange talks

A supporter of WikiLeaks founder Julian Assange sits outside the Ecuadorian Embassy, in London, Friday, June 22, 2012. Assange entered the embassy on Monday in an attempt to gain political asylum to prevent him from being extradited to Sweden to face allegations of sex crimes, which he denies. In a telephone interview with the Australian Broadcasting Corporation (ABC) from inside the embassy, the 40-year-old Australian said he did not know when the decision would be made. (AP Photo/Lefteris Pitarakis)

A supporter of WikiLeaks founder Julian Assange sits outside the Ecuadorian Embassy, in London, Friday, June 22, 2012. Assange entered the embassy on Monday in an attempt to gain political asylum to prevent him from being extradited to Sweden to face allegations of sex crimes, which he denies. In a telephone interview with the Australian Broadcasting Corporation (ABC) from inside the embassy, the 40-year-old Australian said he did not know when the decision would be made. (AP Photo/Lefteris Pitarakis)

This two picture combo shows from left; a Feb. 1, 2012 file photo of WikiLeaks founder Julian Assange as he arrives at the Supreme Court in London, and a June 20, 2012 photo of Ecuador's President Rafael Correa during a meeting at the United Nations Conference on Sustainable Development, or Rio+20, in Rio de Janeiro, Brazil. Correa's objections to what he deems American interventionism in Latin America and his delight in Assange's massive uncorking of U.S. secrets appear to have persuaded the WikiLeaks chief that Ecuador offers his best shot at avoiding extradition to Sweden. But four days after Assange ducked into Ecuador's London embassy seeking political asylum, this South American nation's leader has yet to announce a decision. The choice may not be easy. (left photo - AP Photo/Kirsty Wigglesworth, File; right photo -AP Photo/Victor Caivano, File)

John Pilger, an Australian journalist, broadcaster and documentary maker, talks to members of the media after meeting WikiLeaks founder Julian Assange, at the Ecuadorian Embassy, in London, Friday, June 22, 2012. Assange entered the embassy on Monday in an attempt to gain political asylum to prevent him from being extradited to Sweden to face allegations of sex crimes, which he denies. In a telephone interview with the Australian Broadcasting Corporation (ABC) from inside the embassy, the 40-year-old Australian said he did not know when the decision would be made. (AP Photo/Lefteris Pitarakis)

LONDON (AP) ? Ecuador's embassy in London said Saturday that ambassador Anna Alban was traveling to her country's capital to brief President Rafael Correa on the bizarre request for political asylum made by Wikileaks chief Julian Assange.

Assange took refuge inside the embassy on Tuesday and remains camped out in an office there after his legal options ran out for avoiding extradition from Britain to Sweden, where he is wanted for questioning for alleged sex crimes.

Correa, Ecuador's leftist president, has said his government is considering Assange's request, but has not indicated when a decision will be made.

In a statement, the country's embassy said Saturday that Alban had boarded a flight to Quito to personally brief Correa on the situation.

"While in Ecuador she will be holding a series of meetings with officials at the ministry of foreign affairs before meeting President Correa to personally brief him on Mr. Assange's application for political asylum," the statement said. "She will also fully brief the president on her recent meeting with officials of the U.K. Government."

Speaking Thursday from inside the embassy, Assange said he had made his bid for asylum because the "Ecuadoreans were sympathetic in relation to my struggles." He had previously interviewed Correa, with whom he shares skepticism toward the United States.

"Ecuador presently finds itself in a unique situation and it is important that those responsible making the final decision on Mr. Assange's application are fully briefed on all aspects of the present," the embassy said in its statement.

Assange has been fighting since 2010 to avoid extradition to Sweden, where he is wanted for questioning over alleged sexual assaults on two women. Assange denies the claims, and says the case against him is politically motivated.

Both he and supporters insist that if he was sent to Sweden he would then likely become the target of a U.S. request to extradite him there over allegations linked to his leaking of hundreds of thousands of secret U.S. documents via the secret-spilling WikiLeaks website.

U.S. soldier, Pfc. Bradley Manning, a 24-year-old from Crescent, Oklahoma, has been charged with aiding the enemy by passing the secret files to WikiLeaks and is awaiting trial.

A Virginia grand jury is studying evidence that might link Assange to Manning, but no action has yet been taken.

"We are hoping what I am doing now will draw attention to the underlying issues," Assange told Australian Broadcasting Corp. radio in an interview Thursday.

Correa said his country would discuss the case with Britain, Sweden and the United States before reaching a final decision.

Jeanette Mattsson, a spokeswoman for Sweden's Justice Ministry, on Saturday said that Ecuador's Ambassador to Stockholm had met with two government officials on Thursday to discuss the Swedish judicial system and Assange's case.

While inside the London embassy, Assange remains outside the reach of British authorities ? but police are poised to arrest him the moment he steps foot outside the building.

Police said Assange will be arrested for breaching the terms of his bail, which included an overnight curfew at a registered address.

Assange's lawyer Jennifer Robinson said Saturday that filmmaker Michael Moore has sent Assange a message of support, urging him not to despair.

Robinson posted an email sent by Moore, among supporters who offered money to meet Assange's 200,000 pounds ($316,000) bail, to her Twitter account.

In the message, sent Wednesday, Moore told the WikiLeaks founder it was a crime "that you even have to seek asylum, and I stand with you through this. Do not despair."

___

Associated Press writer Louise Nordstrom in Stockholm contributed to this report

Associated Press

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Video: PRESS Pass with David Maraniss

MTP Political Roundtable

A showdown on Capitol Hill over the Fast & Furious gunwalking controversy prompted a Congressional Committee, in a party-line vote, to cite Attorney General Eric Holder in contempt of Congress. We?ll talk to the chairman of that committee, Rep. Darrell Issa (R-CA), who led the charge as part of our roundtable. Plus, the fight over the Hispanic vote as the debate over immigration policy takes center stage and the very latest on the GOP veepstakes ? what message will Romney try to send with his pick? The rest of our roundtable weighs in: Former Governor Bill Richardson (D-NM); POLITICO?s Senior Political Reporter Jonathan Martin; and NBC News Chief Foreign Affairs Correspondent Andrea Mitchell.

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T-S: Report: California to see ocean rise 6 inches by 2030

Humboldt County, along with the rest of the West Coast, will see an ocean several inches higher in coming decades, with most of California expected to get sea levels a half foot higher by 2030, according a report released Friday.

The study by the National Research Council gives planners their best look yet at how melting ice sheets and warming oceans associated with climate change will raise sea levels along the country's Pacific coast. It is generally consistent with earlier global projections, but takes a closer look at California, Oregon and Washington.

Although the six inches expected for California by 2030 seem minor, the report estimated that sea levels there will be an average of three feet higher by 2100. About 72 percent of the state's coast is covered by sandy cliffs, and the rest includes beaches, sand dunes, bays and estuaries.

The state in recent years has begun to prepare for rising sea levels expected as the result of a warming climate in which ice near polar regions melts faster and warmer ocean water expands. Policies have been developed to force new coastal building and infrastructure projects to factor in sea level rise, but discussions on how to protect existing populations and properties over the next 100 years is just beginning in many regions.

The Humboldt Bay area may be among the more vulnerable in the state. If the sea level rises as anticipated, it could put 7,800 Humboldt County residents and 570 parcels at risk during 100-year

floods, the big floods that happen statistically every 100 years, according to earlier studies. A variety of other impacts come with such a rise in sea levels. Increased erosion could increasingly threaten homes along the McKinleyville bluffs and Big Lagoon and alter North Coast beaches. Flash flooding may increase in intensity and frequency.

Seaside cliffs will be cut back about 30 yards over the next 100 years, and sand dunes will be driven back even more, said Robert A. Dalrymple, a professor of civil engineering at Johns Hopkins University and chairman of the group that wrote the report. Coastal wetlands will be able to keep pace for about 50 years but will eventually be overwhelmed without new sources of sand and room to move inland.

The report noted that dams hold back about one-third of that sand, which once washed into the sea from the Klamath River in Northern California.

Northern California, Oregon and Washington can expect a less dramatic increase -- about four inches by 2030 and two feet by 2100 -- because seismic activity is causing land to rise north of the San Andreas Fault, offsetting increasing sea levels, and drop south of it. The fault runs out to sea at Cape Mendocino.

Oregon has the advantage of tough basalt formations on much of the coast, but long stretches of Washington are low-lying sandy beaches.

?Anything close to the seas is vulnerable,? Dalrymple said.

The most immediate threat over the next few decades will come from periodic ocean-warming El Nino events, said Gary Griggs, director of the Institute for Marine Sciences at the University of California at Santa Cruz, who was one of the scientists assembled by the council to produce the report.

?During those events, sea level is elevated as much as a foot above normal, and then we've got typically larger waves coming in with the high tides,? particularly in the Northwest, he said.

The report noted that some computer models suggest storms will be stronger as global warming progresses. But Dalrymple said there was no clear consensus in scientific literature, and data from ocean buoys showing waves getting bigger in the Northwest don't go back far enough to conclude that trend will continue.

If a major earthquake occurs beneath the Pacific Ocean off Oregon and Washington, in what is known as the Cascadia subduction zone, that would cause the land to drop, allowing sea level to rise another three to six feet immediately, the report said. Such a major temblor occurred 300 years ago, but it becomes more likely as time passes.

The report was commissioned by states and federal agencies looking for detailed information so they can plan for an accelerated rate of erosion along beaches, bluffs and sand dunes that are already crumbling into the sea. It projected that sea level will rise a little less in 2100 than the projections currently used by California officials.

?A lot of the data we had before was worldwide data or has the caveat, 'Can't be used for planning purposes,?' said Susan Hansch, chief deputy director of the California Coastal Commission. ?It all comes down to the better data you have, the better decisions you can make.?

Sea levels rise for two reasons due to global warming.

Warmer water expands, which can cause sea level to rise as many as 23 inches by 2100, according to the Nobel Prize-winning Intergovernmental Panel on Climate Change. Warmer temperatures also cause ice sheets in Greenland and west Antarctica to melt slowly, adding another foot or more to sea levels by 2100, scientists said.

Those estimates, however, were for the planet as a whole. Some places will see higher seas while others will get less dramatic increases.

Globally, sea levels have risen about eight inches over the last century, but the rate has been increasing significantly, said Griggs.

The report summarized published projections and updated it with an analysis of tidal gauge readings and satellite measurements along specific sites on the West Coast.

The Times-Standard contributed to this report.

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ScienceDaily: Biochemistry News

http://www.sciencedaily.com/news/matter_energy/biochemistry/ Read the latest research in biochemistry -- protein structure and function, RNA and DNA, enzymes and biosynthesis and more biochemistry news.en-usFri, 22 Jun 2012 18:35:06 EDTFri, 22 Jun 2012 18:35:06 EDT60http://www.sciencedaily.com/images/logosmall.gifhttp://www.sciencedaily.com/news/matter_energy/biochemistry/ For more science articles, visit ScienceDaily.http://www.sciencedaily.com/releases/2012/06/120619092935.htm A key component found in an ancient anaerobic microorganism may serve as a sensor to detect potentially fatal oxygen, researchers have found. This helps researchers learn more about the function of these components, called iron-sulfur clusters, which occur in different parts of cells in all living creatures.Tue, 19 Jun 2012 09:29:29 EDThttp://www.sciencedaily.com/releases/2012/06/120619092935.htmhttp://www.sciencedaily.com/releases/2012/06/120618153427.htm Scientists are racing to sequence DNA faster and cheaper than ever by passing strands of the genetic material through molecule-sized pores. Now, scientists have adapted this ?nanopore? method to find DNA damage that can lead to mutations and disease.Mon, 18 Jun 2012 15:34:34 EDThttp://www.sciencedaily.com/releases/2012/06/120618153427.htmhttp://www.sciencedaily.com/releases/2012/06/120618111830.htm Overturning two long-held misconceptions about oil production in algae, scientists show that ramping up the microbes' overall metabolism by feeding them more carbon increases oil production as the organisms continue to grow. The findings may point to new ways to turn photosynthetic green algae into tiny "green factories" for producing raw materials for alternative fuels.Mon, 18 Jun 2012 11:18:18 EDThttp://www.sciencedaily.com/releases/2012/06/120618111830.htmhttp://www.sciencedaily.com/releases/2012/06/120616145535.htm The design of a nature-inspired material that can make energy-storing hydrogen gas has gone holistic. Usually, tweaking the design of this particular catalyst -- a work in progress for cheaper, better fuel cells -- results in either faster or more energy efficient production but not both. Now, researchers have found a condition that creates hydrogen faster without a loss in efficiency.Sat, 16 Jun 2012 14:55:55 EDThttp://www.sciencedaily.com/releases/2012/06/120616145535.htmhttp://www.sciencedaily.com/releases/2012/06/120615204741.htm Researchers have engineered nanoparticles that show great promise for the treatment of multiple myeloma (MM), an incurable cancer of the plasma cells in bone marrow.Fri, 15 Jun 2012 20:47:47 EDThttp://www.sciencedaily.com/releases/2012/06/120615204741.htmhttp://www.sciencedaily.com/releases/2012/06/120613153331.htm A powerful color-based imaging technique is making the jump from remote sensing to the operating room. Scientists are working to ensure it performs as well when spotting cancer cells in the body as it does with oil spills in the ocean.Wed, 13 Jun 2012 15:33:33 EDThttp://www.sciencedaily.com/releases/2012/06/120613153331.htmhttp://www.sciencedaily.com/releases/2012/06/120613133341.htm In the not-too-distant future, scientists may be able to use DNA to grow their own specialized materials, thanks to the concept of directed evolution. Scientists have, for the first time, used genetic engineering and molecular evolution to develop the enzymatic synthesis of a semiconductor.Wed, 13 Jun 2012 13:33:33 EDThttp://www.sciencedaily.com/releases/2012/06/120613133341.htmhttp://www.sciencedaily.com/releases/2012/06/120613133150.htm An implantable fuel cell could power neural prosthetics that help patients regain control of limbs. Engineers have developed a fuel cell that runs on the same sugar that powers human cells: glucose. This glucose fuel cell could be used to drive highly efficient brain implants of the future, which could help paralyzed patients move their arms and legs again.Wed, 13 Jun 2012 13:31:31 EDThttp://www.sciencedaily.com/releases/2012/06/120613133150.htmhttp://www.sciencedaily.com/releases/2012/06/120613102130.htm A scientist may be onto an ocean of discovery because of his research into a little sea creature called the mantis shrimp. The research is likely to lead to making ceramics -- today's preferred material for medical implants and military body armour -- many times stronger. The mantis shrimp's can shatter aquarium glass and crab shells alike.Wed, 13 Jun 2012 10:21:21 EDThttp://www.sciencedaily.com/releases/2012/06/120613102130.htmhttp://www.sciencedaily.com/releases/2012/06/120612145139.htm Researchers have created a computational tool to help predict how proteins fold by finding amino acid pairs that are distant in sequence but change together. Protein interactions offer clues to the treatment of disease, including cancer.Tue, 12 Jun 2012 14:51:51 EDThttp://www.sciencedaily.com/releases/2012/06/120612145139.htmhttp://www.sciencedaily.com/releases/2012/06/120612101458.htm A novel porous material that has unique carbon dioxide retention properties has just been developed.Tue, 12 Jun 2012 10:14:14 EDThttp://www.sciencedaily.com/releases/2012/06/120612101458.htmhttp://www.sciencedaily.com/releases/2012/06/120611193636.htm A newly developed carbon nanotube material could help lower the cost of fuel cells, catalytic converters and similar energy-related technologies by delivering a substitute for expensive platinum catalysts.Mon, 11 Jun 2012 19:36:36 EDThttp://www.sciencedaily.com/releases/2012/06/120611193636.htmhttp://www.sciencedaily.com/releases/2012/06/120611105311.htm New groundbreaking research has found that exposure to nanoparticles can have a serious impact on health, linking it to rheumatoid arthritis and the development of other serious autoimmune diseases. The findings have health and safety implications for the manufacture, use and ultimate disposal of nanotechnology products and materials. They also identified new cellular targets for the development of potential drug therapies in combating the development of autoimmune diseases.Mon, 11 Jun 2012 10:53:53 EDThttp://www.sciencedaily.com/releases/2012/06/120611105311.htmhttp://www.sciencedaily.com/releases/2012/06/120611092345.htm Researchers have created a reliable and fast flu-detection test that can be carried in a first-aid kit. The novel prototype device isolates influenza RNA using a combination of magnetics and microfluidics, then amplifies and detects probes bound to the RNA. The technology could lead to real-time tracking of influenza.Mon, 11 Jun 2012 09:23:23 EDThttp://www.sciencedaily.com/releases/2012/06/120611092345.htmhttp://www.sciencedaily.com/releases/2012/06/120610151304.htm Enabling bioengineers to design new molecular machines for nanotechnology applications is one of the possible outcomes of a new study. Scientists have developed a new approach to visualize how proteins assemble, which may also significantly aid our understanding of diseases such as Alzheimer's and Parkinson's, which are caused by errors in assembly.Sun, 10 Jun 2012 15:13:13 EDThttp://www.sciencedaily.com/releases/2012/06/120610151304.htmhttp://www.sciencedaily.com/releases/2012/06/120606155808.htm Using ultrafast, intensely bright pulses of X-rays scientists have obtained the first ever images at room temperature of photosystem II, a protein complex critical for photosynthesis and future artificial photosynthetic systems.Wed, 06 Jun 2012 15:58:58 EDThttp://www.sciencedaily.com/releases/2012/06/120606155808.htmhttp://www.sciencedaily.com/releases/2012/06/120606132316.htm A new voyage into "chemical space" ? occupied not by stars and planets but substances that could become useful in everyday life ? has concluded that scientists have synthesized barely one tenth of one percent of potential medicines. The report estimates that the actual number of these so-called "small molecules" could be one novemdecillion (that's one with 60 zeroes), more than some estimates of the number of stars in the universe.Wed, 06 Jun 2012 13:23:23 EDThttp://www.sciencedaily.com/releases/2012/06/120606132316.htmhttp://www.sciencedaily.com/releases/2012/06/120605121639.htm Halogens particularly chlorine, bromine, and iodine ? have a unique quality which allows them to positively influence the interaction between molecules. This ?halogen bonding? has been employed in the area of materials science for some time, but is only now finding applications in the life sciences.Tue, 05 Jun 2012 12:16:16 EDThttp://www.sciencedaily.com/releases/2012/06/120605121639.htmhttp://www.sciencedaily.com/releases/2012/06/120605102842.htm Researchers have developed a highly sensitive detector of infrared light that can be used in applications ranging from detection of chemical and biochemical weapons from a distance and better airport body scanners to chemical analysis in the laboratory and studying the structure of the universe through new telescopes.Tue, 05 Jun 2012 10:28:28 EDThttp://www.sciencedaily.com/releases/2012/06/120605102842.htmhttp://www.sciencedaily.com/releases/2012/06/120604092858.htm A new microscope enabled scientists to film a fruit fly embryo, in 3D, from when it was about two-and-a-half hours old until it walked away from the microscope as a larva.Mon, 04 Jun 2012 09:28:28 EDThttp://www.sciencedaily.com/releases/2012/06/120604092858.htmhttp://www.sciencedaily.com/releases/2012/06/120603191722.htm A new study suggests that the replication process for DNA -- the genetic instructions for living organisms that is composed of four bases (C, G, A and T) -- is more open to unnatural letters than had previously been thought. An expanded "DNA alphabet" could carry more information than natural DNA, potentially coding for a much wider range of molecules and enabling a variety of powerful applications, from precise molecular probes and nanomachines to useful new life forms.Sun, 03 Jun 2012 19:17:17 EDThttp://www.sciencedaily.com/releases/2012/06/120603191722.htmhttp://www.sciencedaily.com/releases/2012/05/120531165752.htm A laboratory test used to detect disease and perform biological research could be made more than 3 million times more sensitive, according to researchers who combined standard biological tools with a breakthrough in nanotechnology.Thu, 31 May 2012 16:57:57 EDThttp://www.sciencedaily.com/releases/2012/05/120531165752.htmhttp://www.sciencedaily.com/releases/2012/05/120531145728.htm Scientists have demonstrated how the world's most powerful X-ray laser can assist in cracking the structures of biomolecules, and in the processes helped to pioneer critical new investigative avenues in biology.Thu, 31 May 2012 14:57:57 EDThttp://www.sciencedaily.com/releases/2012/05/120531145728.htmhttp://www.sciencedaily.com/releases/2012/05/120531145720.htm Biochemists have designed specialized proteins that assemble themselves to form tiny molecular cages hundreds of times smaller than a single cell. The creation of these miniature structures may be the first step toward developing new methods of drug delivery or even designing artificial vaccines.Thu, 31 May 2012 14:57:57 EDThttp://www.sciencedaily.com/releases/2012/05/120531145720.htmhttp://www.sciencedaily.com/releases/2012/05/120531145630.htm Ultrashort flashes of X-radiation allow atomic structures of macromolecules to be obtained even from tiny protein crystals.Thu, 31 May 2012 14:56:56 EDThttp://www.sciencedaily.com/releases/2012/05/120531145630.htmhttp://www.sciencedaily.com/releases/2012/05/120531102207.htm Our ability to "read" DNA has made tremendous progress in the past few decades, but the ability to understand and alter the genetic code, that is, to "rewrite" the DNA-encoded instructions, has lagged behind. A new study advances our understanding of the genetic code: It proposes a way of effectively introducing numerous carefully planned DNA segments into genomes of living cells and of testing the effects of these changes. New technology speeds up DNA "rewriting" and measures the effects of the changes in living cells.Thu, 31 May 2012 10:22:22 EDThttp://www.sciencedaily.com/releases/2012/05/120531102207.htmhttp://www.sciencedaily.com/releases/2012/05/120530152203.htm Researchers have developed a method for building complex nanostructures out of interlocking DNA "building blocks" that can be programmed to assemble themselves into precisely designed shapes. With further development, the technology could one day enable the creation of new nanoscale devices that deliver drugs directly to disease sites.Wed, 30 May 2012 15:22:22 EDThttp://www.sciencedaily.com/releases/2012/05/120530152203.htmhttp://www.sciencedaily.com/releases/2012/05/120530104034.htm Inexpensive, portable devices that can rapidly screen cells for leukemia or HIV may soon be possible thanks to a chip that can produce three-dimensional focusing of a stream of cells, according to researchers.Wed, 30 May 2012 10:40:40 EDThttp://www.sciencedaily.com/releases/2012/05/120530104034.htmhttp://www.sciencedaily.com/releases/2012/05/120530100041.htm Scientists have engineered cells that behave like AND and OR Boolean logic gates, producing an output based on one or more unique inputs. This feat could eventually help researchers create computers that use cells as tiny circuits.Wed, 30 May 2012 10:00:00 EDThttp://www.sciencedaily.com/releases/2012/05/120530100041.htmhttp://www.sciencedaily.com/releases/2012/05/120529113543.htm An integrated chemical chip has just been developed. An advantage of chemical circuits is that the charge carrier consists of chemical substances with various functions. This means that we now have new opportunities to control and regulate the signal paths of cells in the human body. The chemical chip can control the delivery of the neurotransmitter acetylcholine. This enables chemical control of muscles, which are activated when they come into contact with acetylcholine.Tue, 29 May 2012 11:35:35 EDThttp://www.sciencedaily.com/releases/2012/05/120529113543.htmhttp://www.sciencedaily.com/releases/2012/05/120528154859.htm Physicists have developed a method that models biological cell-to-cell adhesion that could also have industrial applications.Mon, 28 May 2012 15:48:48 EDThttp://www.sciencedaily.com/releases/2012/05/120528154859.htmhttp://www.sciencedaily.com/releases/2012/05/120528100253.htm Scientists have created and imaged the smallest possible five-ringed structure -- about 100,000 times thinner than a human hair. Dubbed 'olympicene', the single molecule was brought to life in a picture thanks to a combination of clever synthetic chemistry and state-of-the-art imaging techniques.Mon, 28 May 2012 10:02:02 EDThttp://www.sciencedaily.com/releases/2012/05/120528100253.htmhttp://www.sciencedaily.com/releases/2012/05/120527153818.htm Multi-walled carbon nanotubes riddled with defects and impurities on the outside could replace some of the expensive platinum catalysts used in fuel cells and metal-air batteries, according to scientists.Sun, 27 May 2012 15:38:38 EDThttp://www.sciencedaily.com/releases/2012/05/120527153818.htmhttp://www.sciencedaily.com/releases/2012/05/120527153718.htm Scientists have developed an ultra-sensitive test that should enable them to detect signs of a disease in its earliest stages.Sun, 27 May 2012 15:37:37 EDThttp://www.sciencedaily.com/releases/2012/05/120527153718.htmhttp://www.sciencedaily.com/releases/2012/05/120525103614.htm Images of the cell's transport pods have revealed a molecular version of the robots from Transformers. Previously, scientists had been able to create and determine the structure of 'cages' formed by parts of the protein coats that encase other types of vesicles, but this study was the first to obtain high-resolution images of complete vesicles, budded from a membrane.Fri, 25 May 2012 10:36:36 EDThttp://www.sciencedaily.com/releases/2012/05/120525103614.htmhttp://www.sciencedaily.com/releases/2012/05/120524143527.htm There's nothing like a new pair of eyeglasses to bring fine details into sharp relief. For scientists who study the large molecules of life from proteins to DNA, the equivalent of new lenses have come in the form of an advanced method for analyzing data from X-ray crystallography experiments.Thu, 24 May 2012 14:35:35 EDThttp://www.sciencedaily.com/releases/2012/05/120524143527.htmhttp://www.sciencedaily.com/releases/2012/05/120524123232.htm Researchers are using nanoparticles to simultaneously deliver proteins and DNA into plant cells. The technology could allow more sophisticated and targeted editing of plant genomes. And that could help researchers develop crops that adapt to changing climates and resist pests.Thu, 24 May 2012 12:32:32 EDThttp://www.sciencedaily.com/releases/2012/05/120524123232.htmhttp://www.sciencedaily.com/releases/2012/05/120524092932.htm Quantum physics and plant biology seem like two branches of science that could not be more different, but surprisingly they may in fact be intimately tied. Scientists have discovered an unusual quantum effect in the earliest stages of photosynthesis.Thu, 24 May 2012 09:29:29 EDThttp://www.sciencedaily.com/releases/2012/05/120524092932.htmhttp://www.sciencedaily.com/releases/2012/05/120523135527.htm Quantum computers may someday revolutionize the information world. But in order for quantum computers at distant locations to communicate with one another, they have to be linked together in a network. While several building blocks for a quantum computer have already been successfully tested in the laboratory, a network requires one additonal component: A reliable interface between computers and information channels. Austrian physicists now report the construction of an efficient and tunable interface for quantum networks.Wed, 23 May 2012 13:55:55 EDThttp://www.sciencedaily.com/releases/2012/05/120523135527.htmhttp://www.sciencedaily.com/releases/2012/05/120522152655.htm Rapid DNA sequencing may soon become a routine part of each individual's medical record, providing enormous information previously sequestered in the human genome's 3 billion nucleotide bases. Recent advances in sequencing technology using a tiny orifice known as a nanopore are covered in a new a article.Tue, 22 May 2012 15:26:26 EDThttp://www.sciencedaily.com/releases/2012/05/120522152655.htmhttp://www.sciencedaily.com/releases/2012/05/120521164104.htm Scientists have synthesized polymers to attach to proteins in order to stabilize them during shipping, storage and other activities. The study findings suggest that these polymers could be useful in stabilizing protein formulations.Mon, 21 May 2012 16:41:41 EDThttp://www.sciencedaily.com/releases/2012/05/120521164104.htmhttp://www.sciencedaily.com/releases/2012/05/120521163751.htm Scientists have devised a method for repeatedly encoding, storing and erasing digital data within the DNA of living cells. In practical terms, they have devised the genetic equivalent of a binary digit -- a "bit" in data parlance.Mon, 21 May 2012 16:37:37 EDThttp://www.sciencedaily.com/releases/2012/05/120521163751.htmhttp://www.sciencedaily.com/releases/2012/05/120521115654.htm Blood tests convey vital medical information, but the sight of a needle often causes anxiety and results take time. A new device however, can reveal much the same information as a traditional blood test in real-time, simply by shining a light through the skin. This portable optical instrument is able to provide high-resolution images of blood coursing through veins without the need for harsh fluorescent dyes.Mon, 21 May 2012 11:56:56 EDThttp://www.sciencedaily.com/releases/2012/05/120521115654.htmhttp://www.sciencedaily.com/releases/2012/05/120521103808.htm The plague, bacterial dysentery, and cholera have one thing in common: These dangerous diseases are caused by bacteria which infect their host using a sophisticated injection apparatus. Through needle-like structures, they release molecular agents into their host cell, thereby evading the immune response. Researchers have now elucidated the structure of such a needle at atomic resolution. Their findings might contribute to drug tailoring and the development of strategies which specifically prevent the infection process.Mon, 21 May 2012 10:38:38 EDThttp://www.sciencedaily.com/releases/2012/05/120521103808.htmhttp://www.sciencedaily.com/releases/2012/05/120518132657.htm Tiny beads may act as minimally invasive glucose sensors for a variety of applications in cell culture systems and tissue engineering.Fri, 18 May 2012 13:26:26 EDThttp://www.sciencedaily.com/releases/2012/05/120518132657.htmhttp://www.sciencedaily.com/releases/2012/05/120518081147.htm Using newly developed imaging technology, chemists have confirmed years of theoretical assumptions about water molecules, the most abundant and one of the most frequently studied substances on Earth.Fri, 18 May 2012 08:11:11 EDThttp://www.sciencedaily.com/releases/2012/05/120518081147.htmhttp://www.sciencedaily.com/releases/2012/05/120517193141.htm Researchers have come closer to solving an old challenge of producing graphene quantum dots of controlled shape and size at large densities, which could revolutionize electronics and optoelectronics.Thu, 17 May 2012 19:31:31 EDThttp://www.sciencedaily.com/releases/2012/05/120517193141.htmhttp://www.sciencedaily.com/releases/2012/05/120517143506.htm Scientists have discovered how adding trace amounts of water can tremendously speed up chemical reactions -? such as hydrogenation and hydrogenolysis ?- in which hydrogen is one of the reactants, or starting materials.Thu, 17 May 2012 14:35:35 EDThttp://www.sciencedaily.com/releases/2012/05/120517143506.htmhttp://www.sciencedaily.com/releases/2012/05/120514104848.htm Three proteins have been found to be involved in the accumulation of fatty acids in plants. The discovery could help plant scientists boost seed oil production in crops. And that could boost the production of biorenewable fuels and chemicals.Mon, 14 May 2012 10:48:48 EDThttp://www.sciencedaily.com/releases/2012/05/120514104848.htmhttp://www.sciencedaily.com/releases/2012/05/120510095622.htm A new approach to generating terahertz radiation will lead to new imaging and sensing applications. The low energy of the radiation means that it can pass through materials that are otherwise opaque, opening up uses in imaging and sensing ? for example, in new security scanners. In practice, however, applications have been difficult to implement.Thu, 10 May 2012 09:56:56 EDThttp://www.sciencedaily.com/releases/2012/05/120510095622.htmhttp://www.sciencedaily.com/releases/2012/05/120509135959.htm To better understand how microRNAs -- small pieces of genetic material -- influence human health and disease, scientists first need to know which microRNAs act upon which genes. To do this scientists developed miR-TRAP, a new easy-to-use method to directly identify microRNA targets in cells.Wed, 09 May 2012 13:59:59 EDThttp://www.sciencedaily.com/releases/2012/05/120509135959.htmhttp://www.sciencedaily.com/releases/2012/05/120508173349.htm Researchers have boosted the efficiency of a novel source of white light called quantum dots more than tenfold, making them of potential interest for commercial applications.Tue, 08 May 2012 17:33:33 EDThttp://www.sciencedaily.com/releases/2012/05/120508173349.htmhttp://www.sciencedaily.com/releases/2012/05/120508152129.htm Chemists have designed a molecular container that can hold drug molecules and increase their solubility, in one case up to nearly 3,000 times.Tue, 08 May 2012 15:21:21 EDThttp://www.sciencedaily.com/releases/2012/05/120508152129.htmhttp://www.sciencedaily.com/releases/2012/05/120503194229.htm Researchers have developed a prototype bioreactor that both stimulates and evaluates tissue as it grows, mimicking natural processes while eliminating the need to stop periodically to cut up samples for analysis.Thu, 03 May 2012 19:42:42 EDThttp://www.sciencedaily.com/releases/2012/05/120503194229.htmhttp://www.sciencedaily.com/releases/2012/05/120503120130.htm A new technique predictably generates complex, wavy shapes and may help improve drug delivery and explain natural patterns from brain folds to bell peppers.Thu, 03 May 2012 12:01:01 EDThttp://www.sciencedaily.com/releases/2012/05/120503120130.htmhttp://www.sciencedaily.com/releases/2012/05/120502132953.htm Liquid crystals, the state of matter that makes possible the flat screen technology now commonly used in televisions and computers, may have some new technological tricks in store.Wed, 02 May 2012 13:29:29 EDThttp://www.sciencedaily.com/releases/2012/05/120502132953.htmhttp://www.sciencedaily.com/releases/2012/05/120502112910.htm A new nanotube super sensor is able to detect subtle differences with a single sniff. For example, the chemical dimethylsulfone is associated with skin cancer. The human nose cannot detect this volatile but it could be detected with the new sensor at concentrations as low as 25 parts per billion.Wed, 02 May 2012 11:29:29 EDThttp://www.sciencedaily.com/releases/2012/05/120502112910.htmhttp://www.sciencedaily.com/releases/2012/05/120502091839.htm A new biomimetic approach to synthesising polymers will offer unprecedented control over the final polymer structure and yield advances in nanomedicine, researchers say.Wed, 02 May 2012 09:18:18 EDThttp://www.sciencedaily.com/releases/2012/05/120502091839.htmhttp://www.sciencedaily.com/releases/2012/05/120501085502.htm Scientists using high-powered microscopes have made a stunning observation of the architecture within a cell ? and identified for the first time how the architecture changes during the formation of gametes, also known as sex cells, in order to successfully complete? the process.Tue, 01 May 2012 08:55:55 EDThttp://www.sciencedaily.com/releases/2012/05/120501085502.htmhttp://www.sciencedaily.com/releases/2012/04/120430151752.htm Biomedical engineers have demonstrated the first all-polymeric bone scaffold that is fully biodegradable and offers significant mechanical support during repair. The technique uses silk fibers to reinforce a silk matrix. Adding microfibers to the scaffolds enhances bone formation and mechanical properties. It could improve repair after accident or disease.Mon, 30 Apr 2012 15:17:17 EDThttp://www.sciencedaily.com/releases/2012/04/120430151752.htm

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Study explains functional links between autism and genes

Thursday, June 21, 2012

A pioneering report of genome-wide gene expression in autism spectrum disorders (ASDs) finds genetic changes that help explain why one person has an ASD and another does not. The study, published by Cell Press on June 21 in The American Journal of Human Genetics, pinpoints ASD risk factors by comparing changes in gene expression with DNA mutation data in the same individuals. This innovative approach is likely to pave the way for future personalized medicine, not just for ASD but also for any disease with a genetic component.

ASDs are a heterogeneous group of developmental conditions characterized by social deficits, difficulty communicating, and repetitive behaviors. ASDs are thought to be highly heritable, meaning that they run in families. However, the genetics of autism are complex.

Researchers have found rare changes in the number of copies of defined genetic regions that associate with ASD. Although there are some hot-spot regions containing these alterations, very few genetic changes are exactly alike. Similarly, no two autistic people share the exact same symptoms. To discover how these genetic changes might affect gene transcription and, thus, the presentation of the disorder, Rui Luo, a graduate student in the Geschwind lab at UCLA, studied 244 families in which one child (the proband) was affected with an ASD and one was not.

In addition to identifying several potential new regions where copy-number variants (CNVs) are associated with ASDs, Geschwind's team found genes within these regions to be significantly misregulated in ASD children compared with their unaffected siblings. "Strikingly, we observed a higher incidence of haploinsufficient genes in the rare CNVs in probands than in those of siblings, strongly indicating a functional impact of these CNVs on expression," says Geschwind. Haploinsuffiency occurs when only one copy of a gene is functional; the result is that the body cannot produce a normal amount of protein. The researchers also found a significant enrichment of misexpressed genes in neural-related pathways in ASD children. Previous research has found that these pathways include other genetic variants associated with autism, which Geschwind explains further legitimizes the present findings.

###

Cell Press: http://www.cellpress.com

Thanks to Cell Press for this article.

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Clinton: family planning key to sustainability

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Richard's Real Estate and Urban Economics Blog: Vicky Been on ...

Richard Green is a professor in the Sol Price School of Public Policy and the Marshall School of Business at the University of Southern California. This blog will feature commentary on the current state of housing, commercial real estate, mortgage finance, and urban development around the world. It may also at times have ruminations about graduate business education.

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